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For most people using tirzepatide at home, the upper arm is best reserved as a backup option when someone else can administer the injection or when both primary sites need a rest

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Losing weight often involves losing some muscle along with fat, and since muscle burns more calories than fat, your daily energy expenditure drops further

Clinical trials indicate that individuals taking a weekly dose of semaglutide can expect an average weight loss of 5-10% of their body weight over several months