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Caffeine, on the other hand, is primarily metabolized by the liver using a process known as cytochrome metabolic pathways, specifically the CYP1A2 enzyme

10.1016/j.pcd.2019.05.001 [EL 2

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Evidence for separate roles Several lines of evidence support the notion of distinct roles for peripheral and central GLP-1 in appetite regulation: Differential breakdown: Peripheral GLP-1 has a very short half-life in the blood (around two minutes) due to enzymatic degradation
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