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goal usually 25-250 cc/hour Diffusion movement of solutes from high to low concentration Dialysate runs countercurrent through semipermeable membrane Typical dialysate composition normal sodium, magnesium, low potassium, no creatinine, no BUN, high bicarbonate Does not remove fluid There are 3 types of RRT: iHD (intermittent hemodialysis), CRRT (continuous renal replacement therapy), SLEDD (slow low efficiency daily diafiltration) None have been shown to be superior in normotensive patients iHD can remove potassium and toxins more quickly SLEDD and CRRT are equivalent and preferred for hypotensive patients