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They help break the cycle of constant hunger and cravings that makes weight loss so challenging for many people

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Renal function was shown to have a neutral effect on the half-life of semaglutide, and similarly, hemodialysis did not affect the pharmacokinetics of this drug

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Keywords: glucagon-like peptide-1 receptor agonist (GLP-1RA), incretin based therapy, glucose-depent insulinotropic peptide (GIP), dual agonists, tirzepatide, type 2 diabetes Introduction Recent data from the International Diabetes Foundation (IDF) Diabetes World Atlas released at the end of 2021 shows a consistently rising prevalence of type 2 diabetes (T2D) with different incidence increases in various regions of the world