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Hepatic transporter protein function is then decreased, which leads to both an increase in hepatic bile acid chelation and persistent inflammation

British journal of pharmacology, 2012, 166(1), 2741

The distinction is clinically important: if you experience nausea, vomiting, or abdominal discomfort, these are recognized tirzepatide-related effects that may improve with time or dose adjustment

2 In general, motor symptoms gradually worsen over time

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