bcbs federal glp 1 coverage GLP-1 for obesity treatment in 13 US states' Medicaid programs blue cross blue shield fep

Current US prescribing information lists personal or family history of medullary thyroid carcinoma (MTC), MEN 2, and previous serious hypersensitivity to tirzepatide or its ingredients as strict contraindications

10.1016/j.endmts.2024.100162 Endocrine Metab Sci

Thyroid tumors: Some GLP-1 medications carry a warning about a potential risk of thyroid C-cell tumors

As the use of GLP-1 therapies continues to expand, recognition of emerging safety signals in real-world data may support earlier clinical awareness, while formal causality determination remains the responsibility of marketing authorization holders and regulatory authorities

DOI: 10.1038/s41591-022-02026-4