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This study, along with other studies involving the PLID, will have a significant impact on the treatment of patients with type-2 diabetes in the future

The menopause results come from a post-hoc analysis, meaning researchers went back and examined the trial data by menopausal status after the studies were completed

This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors

The GLP-1 analogs, semaglutide and liraglutide, delay the progression of atherosclerosis by regulating inflammatory pathways in low-density lipoprotein receptor-deficient (LDLr -/- ) and apolipoprotein E-deficient (ApoE -/- ) mice [16]

In this regard, the ability of various phytochemicals to enhance sirtuin activity and restore dysregulated metabolic signaling further supports sirtuin modulation as a promising strategy for phytochemical-based therapeutic intervention in PD