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Current clinical practice considerations emphasize the importance of ophthalmologic screening before initiating GLP-1 therapy in patients with longstanding diabetes and implementing more gradual titration schedules in those with known retinal disease to minimize the risk of early worsening

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To view or add a comment, sign in The Bucket With a Hole: Why NAD+ Supplementation Fails Without Addressing CD38 NAD+ depletion in aging and chronic disease is driven less by insufficient synthesis than by active inflammatory drain through CD38 a NADase upregulated by NF-kB-mediated immune signaling

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Action and function of Akkermansia muciniphila in microbiome ecology, health and disease