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Hydration becomes more critical once you start semaglutide because reduced appetite can lead patients to forget drinking enough water

The most widely used ones right now are semaglutide (sold as Ozempic for diabetes management and Wegovy for weight loss) and tirzepatide, which targets both GLP-1 and a second hormone called GIP (Mounjaro for diabetes, Zepbound for weight loss)

Coordination Training Learning to coordinate and relax the pelvic floor muscles can help with complete bowel evacuation, especially if tension is contributing to constipation

Several double-blind clinical trials of GLP-1R agonists including exenatide in PD and other neurodegenerative diseases are already underway or are about to be initiated

Caplan, A