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The federal government will pick up the majority of that cost, about $25 billion for Medicare and $11 billion for Medicaid over 10 years, government officials said Tuesday
Who Should Consider Alternative Approaches and When Provider Guidance Matters Most Patients experiencing inadequate weight loss on optimized monotherapy, intolerance to side effects, or specific metabolic conditions (e.g., type 2 diabetes requiring dual GLP-1/GIP benefit) are candidates for evidence-based alternatives

While metformin has long served as the standard first-line therapy, many clinicians are now reconsidering whether a metformin-first and wait strategy is enough for this higher-risk population

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Fiber does not act like a drug version of GLP-1
