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The Science Behind Better Sleep Research Findings Multiple studies show promising results for GLP-1 therapy and sleep: A 2024 systematic review found that GLP-1 medications significantly reduced sleep apnea severity scores by an average of 6-12 events per hour compared to placebo

Li et al., 2022)

For individuals paying out-of-pocket, a 30-day supply of Qsymia costs about $274

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The 68week STEP 4 trial used a withdrawal design: after a 20week runin period with openlabel semaglutide, participants were randomized to continued semaglutide 2.4 mg versus switch to placebo (both as adjunct to lifestyle intervention) (Figure S1)