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2 The effects of the DPP-4 inhibitors are glucose-dependent and so there is a low risk of hypoglycaemia

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Gastric motility is generally expected to return to normal once the effect of the medication wears off

In addition, participants on orforglipron 36 mg lost 19.7 pounds (9.2%) compared to 11 pounds (5.3%) with oral semaglutide 14 mg, representing a 73.6% greater relative weight loss