fda glp-1 compounding warning september 2025 Safe use of compounded GLP products Beyond the Headlines: FDA Warning

This effect was achieved by reversing myelin damage and ameliorating degenerative changes in the sciatic nerve of diabetic rats [82]

The uncontrollable neuroinflammation initiated by activated microglia elicits a prominent secondary injury cascade including demyelination, the loss of neurons, and glial accumulation around the originally injured site associated with irreversible neurological functional disorders [5]

Dual-Indication Prescribing Several weight loss medications have FDA-approved indications beyond obesity

Physical therapists will play an integral role in the long-term success of patients as maintenance of the health benefits derived from GLP-1 agonist therapy necessitates lifestyle modifications like increasing activity levels and engaging in regular aerobic and resistance exercise

This underscores the importance of a carefully managed discontinuation plan, which is yet to be standardized in clinical guidelines