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[Google Scholar] 96.Hagel JM, Krizevski R, Marsolais F, Lewinsohn E, Facchini PJ

Uma vez na circulao, o GLP-1 possui uma meia vida de menos que 2 minutos, devido rpida degradao pela enzima dipeptidil peptidase 4

Collaborative discussions between healthcare providers and patients are crucial to determine the appropriate dosage that balances effectiveness and tolerability

1,2 If initiating a GLP-1 RA in a patient with T2D for glucose-lowering effect and/or for organ protection in a patient on background DPP-4 inhibitor therapy, it is recommended that the DPP-4 inhibitor be discontinued

After four weeks at 0.25 mg, doses increase in steps every four weeks, following the pattern below