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This phenomenon was observed in the famous Minnesota Starvation Diet, where men in WW2 concentration camps were starved and were noted to have intrusive food thoughts, among many other side effects

[99], which involved transplantations of fecal microbiota obtained from depressed patients into a microbiota-depleted antibiotic rat model, the animals developed depressive-like symptoms, which were manifested by behavioral differences such as decreased sucrose intake in the sucrose preference test, a lower number of entries to an open arm in the elevated plus-maze test, and an increase in a plasma kynurenine/tryptophan ratio

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Baviera M., Genovese S., Lepore V., Colacioppo P., Robusto F., Tettamanti M., DEttorre A., Avanzini F., Fortino I., Nicolucci A., et al

Diabetes Complications 35, 107840

Wegovy typically produces greater weight loss because of the higher dose