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Nicholas Moore from the Universit de Bordeaux notes: Aldosterone antagonists (eg, spironolactone) are associated with an increased risk of GI bleeding and possibly impaired healing of gastric or duodenal erosions

Doses become larger than intended, increasing the risk of side effects and accelerating through your dose escalation faster than planned

The current role of SGLT2 inhibitors in type 2 diabetes and beyond: a narrative review

However, the medication is currently in phase 3 clinical trials to determine its long-term safety profile

Encapsulation of exenatide in poly-(d,l-lactide- co -glycolide) microspheres produced an investigational long-acting once-weekly formulation for type 2 diabetes