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It is a synthetic 39-amino acid peptide that acts as an agonist at both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R), producing synergistic metabolic effects that exceed those of selective GLP-1 agonists in clinical trials

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Retrieved from Lilly-i

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Excess weight is one of the leading risk factors for OSA, as fat deposits around the neck can obstruct airflow

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Tirzepatide versus retatrutide: understanding the dose difference Retatrutide is the next-generation GLP-1 compound that adds a third receptor target to tirzepatide dual-agonist mechanism

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doi: 10.3390/nu15224809 Retrieved from Jastreboff, A

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