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NEWS/UPDATES RetatrutideA Game Changer in Obesity Pharmacotherapy

Most patients lose 2-8 pounds in month one, though some see minimal change during dose escalation

Important Considerations While combining Wegovy and metformin can be beneficial, there are some important factors to consider: Side Effects: Both medications can cause side effects

Data from animal models and preclinical studies indicate that GLP1RA may help restore dopamine levels, prevent dopaminergic loss, reduce neuronal degeneration, and alleviate both motor and non-motor symptoms of Parkinsons disease

Glp1r:GnasWT (black, n = n = 3 slices, 3 mice), GnasKO (red, n = 7 slices, 3 mice), Glp1r:GnasWT+FR (blue, n = 4 slices, 2 mice), GnasKO+FR (purple, n = 4 slices, 3 mice)