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Description
Unlike semaglutide, its not a peptide, which makes it more stable in the stomach and easier for the gut to absorb

For extra help, Gupta says most people are OK to use a gentle laxative or stool softener
Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor

These differences affect patient care in important ways

NICE has not issued guidance on retatrutide, as it cannot appraise medicines that do not hold a UK marketing authorisation
