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Aging Cell 22 , 13818 (2023)

-catenin siRNA partially blocked the signal activation induced by liraglutide and weakened the promoting effect of liraglutide on MC3T3-E1 cells (Wu et al., 2017) (Figure 1)

Functional changes in the microbiota of low-gene-count patients primarily consist of a decrease in butyrate-producing bacteria and an increase in the ratio of Akkermansia to Ruminococcus gnavus , which lead to decreased methane production potential, decreased hydrogen production potential, enhanced mucus degradation, and increased peroxidase activity (le Chatelier et al., 2013)

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