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If your kidney function is already compromised, the risk of dehydration or electrolyte imbalance is higher

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FDA approves Ozempic to reduce the risk of kidney disease worsening, kidney failure and death due to CV disease in adults with type 2 diabetes and CKD Novo Nordisk Novo Nordisk announced that the FDA has approved Ozempic (semaglutide injection) to reduce the risk of kidney disease worsening, kidney failure (end-stage kidney disease), and death due to cardiovascular disease in adults with type 2 diabetes and chronic kidney disease (CKD)

The short answer: medical experts strongly advise against this combination due to serious drug interaction risks and overlapping cardiovascular stimulation