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Bisphosphonates (alendronate, risedronate): Used for osteoporosis, these medications are known to cause esophageal irritation and must be taken upright with a full glass of water

GLP-1 agonists regulate both appetite and blood sugar in ways that can significantly aid weight loss, particularly in individuals with obesity

This slower titration may improve short-term tolerability, but it is important to stress that this method has not been studied in large clinical trials

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