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Disrupted sleep and chronically elevated cortisol are known upstream contributors that reduce L-cell sensitivity and dampen hormonal responsiveness

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A considerable proportion of children exhibit poor working memory, manifesting as inattentiveness, distractibility, and difficulty completing tasks requiring sustained focus

The highest level of GLP-1R expressing cells, detected by transgene expression (Cork et al., 2015), in situ hybridization (Merchenthaler et al., 1999