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Patient-centered medicine is the best medicine, he says
Is it worth paying more for combination formulations

Importance of Aggregate Analysis Aggregates may: Alter pharmacokinetic behavior Increase immunogenicity risk Reduce therapeutic potency Impact formulation stability Analytical Challenges Aggregate characterization often requires: Orthogonal analytical methods SEC coupled with MS Native mass spectrometry Stability-indicating analytical workflows Using multiple complementary techniques improves confidence in impurity detection and biosimilar comparability

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10.1210/edrv.18.6.0318 Endocr Rev
