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We need to treat it like one, just like we treat hypertension or high cholesterol. Two GLP-1 agonists and one dual GIP/GLP-1 agonist are currently FDA-approved to treat obesity

However, while BMI can indicate obesity, its not always an accurate measure of health for some people, such as those with more muscle

[1] [2] The medication is administered as a once-weekly subcutaneous injection, typically on the same day each week to maintain consistent therapeutic levels in your bloodstream

Homeostatic system, controlled by hypothalamus and brain stem, stimulates food intake in case of low energy stores (16)

Now we've talked about training close to failure and mechanical tension and all that