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To achieve the enrollment target for the substudy (approximately 100 participants), the main study was overenrolled ( n = 338 versus planned n = 300)
This includes metabolic labs, cardiac risk evaluation, medication review, and an anesthesia assessment
These actions lower blood glucose levels, which contributes to weight loss and improved blood sugar control
Together, these drugs help regulate fluid balance, blood pressure, and cardiac workload in patients with certain cardiovascular and renal conditions
