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Keywords: Incretins, Hypothalamus, Electrophysiology, Immunohistochemistry, Appetite, Obesity GRAPHICAL ABSTRACT INTRODUCTION Glucagon-like peptide-1 (GLP-1) belongs to the incretin family, renowned for its glucose-dependent insulinotropic and appetite-suppressing functions [1]

[Google Scholar] 4.Savino F., Benetti S., Liguori S.A., Sorrenti M., Montezemolo L.C.D

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For context, in other studies with different study designs and subject-level differences, researchers have documented weight reductions of up to ~5% with other drugs, e.g., 72% with 2 mg semaglutide after treatment periods of up to 68 weeks