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Other potential concerns associated with tirzepatide: Birth control interactions: Tirzepatide may reduce the effectiveness of oral hormonal birth control, such as desogestrel, ethinyl estradiol, and levonorgestrel, so it is recommended to switch to non-oral contraceptives before starting tirzepatide

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These effects create synergistic benefits that exceed what would be expected from simple addition of single-pathway therapies

Cardiovascular risks and benefits of medications used for weight loss