tirzepatide adolescent obesity trial A Study of in Adolescents With and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2) Tirzepatide as Compared with Semaglutide

Description

Design, Setting, and Participants Randomized phase 3 clinical trial conducted at 45 medical research centers and hospitals in 8 countries (enrollment from August 30, 2019, to March 20, 2020

Based on current clinical evidence, the rough ordering from largest to smallest weight-loss effect is: Tirzepatide highest average weight loss Semaglutide significant weight loss Tesamorelin moderate weight loss, primarily through visceral fat reduction AOD-9604 primarily body composition effects MOTS-c primarily metabolic and energy effects rather than pure weight reduction AOD-9604 and MOTS-c are generally not considered replacements for GLP-1 medications in patients seeking substantial weight reduction

The average weight loss offered by tirzepatide has been proven to be superior to semaglutide in clinical trials

Flooding is now possible along the Nooksack River in Whatcom County as a Pineapple Express brings heavy rain to both the mountains and the lowlands over several days in Western Washington.Current forecasts have caught the attention of Whatcom County officials, who told The Bellingham Herald that they are watching the Nooksack River and have action plans in place.Earlier forecasts indicated that the warm atmospheric rivers most intense rain would fall in southern British Columbia, but Wednesday estimates from the Northwes