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As we demonstrated that the lifespan of glp-1(-) and fem-3(-) worms is contingent upon DAF-16 activation, we explored whether ectopically activating DAF-16 in mog-3(-) worms could extend their lifespan
However, cross-reactivity is possible, and any switch should be undertaken under specialist supervision with careful monitoring for recurrence of symptoms
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If you are on hormone replacement therapy, the interaction is worth discussing with your prescriber
