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Vear A, Heneka MT, Clemmensen C (2025) Incretin-based therapeutics for the treatment of neurodegenerative diseases

[DOI] [PubMed] [Google Scholar] 26.Hettema EH, Tabak HF

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But it also can worsen the disorder and exacerbate other symptoms, such as insulin resistance , irregular periods, excess androgen (aka male hormone) levels, and infertility

Effects of GLP-1 and GIP receptor agonists include: Stimulating insulin secretion in response to food (glucose-dependent) Reducing inappropriate glucagon release, lowering hepatic glucose output (GLP-1 enhances the sensitivity of alpha cells to glucose , resulting in more glucose-appropriate glucagon secretion) When blood glucose is high, insulin secretion is stimulated and glucagon secretion is inhibited