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GLP-1Rs were expressed in five of six skin biopsies from psoriasis plaques, in one of six biopsies from unaffected psoriatic skin, and in one of six biopsies from healthy skin

With careful monitoring and support from healthcare providers, semaglutide and lisinopril can be a valuable part of a balanced, effective treatment plan for those needing help in both areas

rather, these findings can help clinicians anticipate which patients may benefit from earlier combination approaches or closer monitoring during dose titration