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SGLT2 inhibitors and cardiovascular risk: lessons learned from the EMPA-REG OUTCOME Study

Because it can affect your gastrointestinal system and blood sugar response, starting at the full dose immediately can increase the risk of side effects

However, if you find that its no longer working as well as it used to, there are plenty of alternative treatments and strategies to explore

In May 2025, the comedian posted on Instagram about her transformation, explicitly referencing the medication in her caption
