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Others have found injections to be a barrier
Samms RJ, Christe ME, Collins KA, Pirro V, Droz BA, Holland AK, et al
The magnitude varies significantly between individuals: STEP 4 Trial : Participants who stopped semaglutide after 20 weeks regained approximately 7% body weight over next 48 weeks (compared to losing an additional 8% who continued medication) Real-World Studies : Variable outcomes
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Additionally, for individuals with type 2 diabetes, obesity, and heart failure with preserved ejection fraction, GLP-1 receptor agonists are advised to manage glucose and alleviate heart failure symptoms
