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There was no significant difference in oral bioavailability of semaglutide in healthy subjects and subjects with type 2 diabetes

F., Kelly J

Total weekly drug exposure (AUC) is the same, so weight-loss outcomes should be similar over a several-month window

Calorie needs vary by individual and are best agreed with your prescriber or doctor based on your health history and goals
Salvatore T, Galiero R, Caturano A et al (2022) An overview of the cardiorenal protective mechanisms of SGLT2 inhibitors
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