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If tirzepatide can restore thermogenic capacity and adipose flexibility in affected depots, it may address one of the most entrenched barriers to effective management of the disease

Obesity Reviews: An Official Journal of the International Association for the Study of Obesity, 22 Suppl 4 (Suppl 4), e13256

These actions align with key pathogenic nodes of lipedema biology, strengthening the mechanistic rationale for its therapeutic exploration

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