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Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age

Discussion The results of the current meta-analysis, that included 60,080 patients with T2DM, 14,804 of whom without established CV disease, demonstrate that GLP-1RA reduce the risk of MACE by 14% in the overall diabetic population, with an apparently greater effect in patients with known CV disease as compared with those without established CV disease (16% vs 6% reduction, respectively)

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Healthcare providers monitor your response to the injections closely to ensure your comfort and manage any side effects that may arise

Although nausea and reduced food intake can occur with some GLP-1 receptor agonists, many studies showed reduced alcohol and drug-seeking behaviors even when substances were administered intravenously, suggesting the effects go beyond simple appetite suppression