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The intersection between insulin resistance, hepatic steatosis, and progressive fibrosis is now clearer than ever, making early identification and multidisciplinary management crucial

We need to learn what these medications are capable of, said Pratley

(Though not as much wine.) When I went on vacation to Sicily, I had no trouble going hedonist mode to the point of insufferability

EASL-EASD-EASO clinical practice guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

Try a different medication: If you want to keep taking a weight-loss medication but the cost or side effects make GLP-1s a no-go, there are other options out there such as Qsymia and Contrave and your clinician may be able to recommend and prescribe a different weight-loss medication