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In Phase 2 trials, participants on the highest dose (12mg weekly) lost an average of 24.2% of their body weight over 48 weeks, results that surpass both semaglutide and tirzepatide at their respective trial endpoints

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This medicine can help you lose more weight and may also improve your heart and kidney health

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Reactions Weekly 2070, 499 (2025).

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Overview of Tirzepatide Tirzepatide is a dual-agonist research peptide , interacting with: GLP-1 receptors GIP receptors Its more focused receptor profile has made Tirzepatide a reference compound in many peptide studies and comparative analyses

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