3 month tirzepatide high dose Dosing Restarting Tirzepatide After a Month:

The key difference is what the FDA says you can use it for

In the first one to two weeks after stopping, most patients still experience some appetite suppression and blood sugar regulation

But on the other hand, if the agency sides with the compounders and reverses its decision on tirzepatides shortage status, it risks opening itself up to lawsuits from big pharmaceutical companies like Novo Nordisk and Eli Lilly, companies whose market dominance could be undercut by the production of compounded versions and who made billions of dollars in production investments to keep up with demand

[1] When you skip a week of tirzepatide, several physiological changes may occur

Or if you are losing weight too rapidly (more than 1-2% of body weight per week consistently), which increases the risk of gallstones, muscle loss, and metabolic disruption