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In a study of more than 1,600 adults with type 2 diabetes, those who received the highest dose of orforglipron on average shed 10.5% of their weight.

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UCLA followed 173 RA patients with a BMI of 27 or higher who took semaglutide or tirzepatide, against 42 who were prescribed it but never started

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It is also used to lower the risk of worsening of kidney disease, kidney failure (end-stage kidney disease), and death caused by heart or blood vessel disease in patients with type 2 diabetes and chronic kidney disease

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