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Do not use the pen if: It was exposed to temperatures above 30C It has been frozen The solution appears cloudy, discoloured, or contains particles You are unsure of the duration or temperature of exposure 5

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Turn the dose selector to the flow check symbol, then press the dose button and confirm that a drop appears at the needle tip this ensures the pen is primed and ready for use

Semaglutide is generally safe, and for many people, the benefits are greater than the possible long-term risks