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Signs of frank nutrient deficiency include fatigue beyond expected levels, excessive hair loss, skin flakiness or itching, muscle weakness, poor wound healing, and unusual bruising [59]

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The most common side effects include: Constipation or diarrhea Dehydration Nausea Hair loss Increased risk of pancreatitis Mood changes Beyond these side effects, patients may be drastically reducing their caloric intakeits advised to screen them for micronutrient deficiencies and supplement accordingly
