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Description
Permite mimetizar a fisiologia da secreo insulnica ao estimular uma secreo rpida e de curta durao de insulina tentando reproduzir a primeira fase de secreo, a qual encontra-se suprimida no diabetes estabelecido (DORNHORST, 2001
Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this Article
Accordingly, preclinical research has established crucial mechanisms of neurotransmission within the reward system that differentiate between motivational aspects of reward (i.e., dopamine) rather than the pleasure (i.e., opioids and endocannabinoids) itself (Berridge & Kringelbach, 2015
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doi: 10.2337/dc11-s231 [DOI] [PMC free article] [PubMed] [Google Scholar] 28
