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Avantika Waring, MD, is the Chief Medical Officer at 9amHealth, bringing over fifteen years of clinical and leadership experience

Acknowledgments: During the preparation of this manuscript/study, the author(s) used OpenAI GPT-4 and Perplexity AI GPT-4 for the purposes of extracting relevant quotations from full text articles, analyzing risk of bias for studies, generating a summary table, and generating a graphical abstract

Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity

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PlexusDx patients combining semaglutide therapy with structured health coaching sometimes report this compounding effect