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Description
Systematic assessment of animal studies revealed a potential association of several molecular pathways, including AMPK-, SIRT1, FDX, PI3K/AKT, endothelial adhesion molecules (VCAM, ICAM, and E-selectin), STAR, and CYP17A1, with the therapeutic effects of GLP-1 RAs and SGLT2is in PCOS
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11-13 GLP-1 receptors are expressed in multiple tissues, therefore, GLP-1RAs have multiple mechanisms of action (Figure 2)
