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By week three or four, you have overlapping layers of medication building toward what pharmacologists call steady state, the point where the amount entering your system equals the amount being eliminated

Commercial launch follows 13 months later = realistic availability Q1Q2 2028

doi: 10.1038/s41593-024-01696-2 [DOI] [PMC free article] [PubMed] [Google Scholar] Trinko JR, Foscue E, Kong EM, Basu A, Corstens AM, Thompson SL, Kaye AP, Taylor JR, DiLeone RJ

Normal side effects are mild to moderate, improve over time, and don't prevent eating or hydrating

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