sglt2 inhibitors and glp-1 receptor agonists inhibitors: a couple at last? SGLT2 vs GLP-1 for CKD:

R.AngellottiE.MauroC.et al (2017)

doi: 10.1007/s00125-006-0510-2

Nature website

One reason these drugs are so effective in treating obesity could be that they address the underlying addiction

1 Introduction Incretin peptides are secreted from the intestine after nutrient ingestion and enhance glucose-stimulated insulin secretion ( 2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D ( The mechanism underlying the impressive weight loss potential of GLP-1R agonists is primarily, if not exclusively, mediated by a reduction in energy intake