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Evidencia clnica El programa de estudios SURPASS ha sido fundamental para establecer el perfil clnico de tirzepatida, el primer agonista dual GLP-1/GIP aprobado para la DM2

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As patents are provided with 20 years of protection from the date of filing once granted, these patents should technically expire on March 20, 2026 (see Figure 8)

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Curcumin also enhances TP53 expression, which is inhibited by miR-125a-5p (Gao et al., 2014)
