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While you cannot eliminate the risk entirely, certain practices help reduce severity: start with the lowest dose (0.25 mg weekly), escalate slowly, maintain excellent hydration, eat smaller meals, and avoid high-fat and high-fiber foods during the first 4 weeks

In the coming years, patients and providers will have the options of newly launched biosimilars, novel GLP-1s, combination drugs, and approvals for allied indications

Diabetologia (1999) 42:3269

Medium term

As discussed below, GLP-1 RAs have beneficial effects on atherosclerotic cardiovascular disease, heart failure, renal disease, metabolic dysfunction associated steatotic liver disease (MASLD), osteoarthritis, etc